Turmeric is the dried powdered rhizome derived from the plant Curcuma Longa . Curcuminoids constitute around 5% of most turmeric preparations and can be readily isolated from the plant [1]. There has recently been considerable interest in curcumin, [(1E,6E)-1,7-bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-diene 3,5-dione] the primary active ingredient in turmeric, because it has been shown to have anticancer[1,2,3a,3b], antioxidant [4,5], anti-inflammatory [6], anti-Alzheimer's disease activity [7,8] antibacterial activity [9] and cardioprotective benefits [10,11]. Curcumin's anti- cancer properties are a result of it's ability to modulate and work on multiple cell signaling pathways, including cell cycle (cyclin D1 and cyclin E), apoptosis (activation of caspases and down-regulation of antiapoptotic gene products), reduces proliferation (HER-2, EGFR, and AP-1), survival (PI3K/AKT pathway), reduces invasion (MMP-9 and adhesion mols.), angiogenesis (VEGF), metastasis (CXCR-4) and reduces inflammation (NF-k?, TNF, IL-6, IL-1, COX-2, and 5-LOX) [1,2,3,4]. Curcumin has multiple neuro-protective mechanisms including inhibition of inflammation, suppression of (Aymyloid) A? production, reduction of reactive oxygen species by chelating metals, inhibition of stress pathways and induction of heat shock proteins [7]. There is evidence that that turmeric consumption in the diet (South East Asian) has been correlated with a reduced incidence of Alzheimer's disease [7] and colon cancer [12]. It is thus evident from the above that the making curcumin and/or curcuminoids and/or turmeric components intake an integral part of the American diet will have a huge positive impact on American health and healthcare. Turmeric, Curcumin and Curcuminoids are Generally Regarded as Safe for human consumption by the Unites States Food and Drug Administration. There have been over 2600 peer reviewed articles published in English since 1966, ˜19 review articles have been written in the last ten years and curcumin has been or is currently being used in over 17 clinical trials [4]