| The active component curcumin
in the spice turmeric is shown to prevent and retard cancer in hundreds
of studies and research reports. Many of the methods by which carcinogenesis
(attack of carcinogens on the DNA and cellular structure) progresses
has been shown to be retarded or short circuited by turmeric. A powerful
carcinogenic agent TPA (tissue polypeptide antigen) is known to cause cancer
by increasing the production of a substance in the body called protein
kinase. Turmeric appears to suppress the production of protein kinase.
Turmeric is also shown to lower the levels of oncogen which is a cancer
causing gene called c-jun. A team of scientists not only demonstrated these
suppressive effects but caused a 99% inhibition of TPA induced tumors on
rodents.
It is obvious that turmeric
is shutting of some of the cancer causing pathways and probably blocking
of malignant tumors at the initiation, promotion and progression stage
itself. Turmeric is capable of slowing or preventing genetic mutation in
cells that are risk factors for cancer. Mutation is a genetic change
in the DNA - Deoxyribonucleic acid of a cell that gets passed on to future
generations of the cells in the process of cell division. Although not
all DNA mutations are carcinogenic cancer has always followed DNA mutation.
Couple of important studies
has dramatically indicated that this cancer causing DNA mutation pathway
can be closed by turmeric. In one study mutagenic changes in the bone marrow
of mice were significantly decreased by administration of turmeric extract.
Another study was dramatic because it was done on people. Normally such
studies are never done on people as it is illegal and unethical to inject
people with carcinogenic agents as in the case of animals used for laboratory
studies. Smokers are injecting themselves with wide range of carcinogenic
agents. A study was done on 100 smokers in India who refused to quit against
all warnings. They were given turmeric extract pill for 30 days (Though
diet in India regularly contains turmeric that is not sufficient). During
this period there was a startling 40% reduction in the urinary extraction
of tobacco related mutagens - a byproduct of cell/DNA mutation. Clearly
turmeric -curcumin detoxified enough carcinogens in the lungs to cause
such a reduction of mutation process.
Turmeric tops the short list
of really powerful cancer preventive agents. Many government funded agencies
like Nation Cancer Institute, Medline Plus and American Cancer Institute
have recognized turmeric as one of the best means of prevention against
cancer.
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