The rhizome (root)
of turmeric ( Curcuma longa Linn.) has long been used in traditional
Asian medicine to treat gastrointestinal upset, arthritic pain, and "low
energy." Laboratory and animal research has demonstrated anti-inflammatory,
antioxidant, and anti-cancer properties of turmeric and its constituent
curcumin. Preliminary human evidence, albeit poor quality, suggests possible
efficacy in the management of dyspepsia (heartburn), hyperlipidemia (high
cholesterol), and scabies (when used on the skin).
Evidence Return to top
These uses have been tested
in humans or animals. Safety and effectiveness have not always been proven.
Some of these conditions are potentially serious, and should be evaluated
by a qualified healthcare provider.
Uses based on scientific
evidence Grade *
Blood clot prevention
Early research suggests that
turmeric may prevent the formation of blood clots. However, more research
is needed before turmeric can be recommended for these conditions.
C
Cancer
Several early animal and
laboratory studies report anti-cancer (colon, skin, breast) properties
of curcumin. Many mechanisms have been considered, including antioxidant
activity, anti-angiogenesis (prevention of new blood vessel growth), and
direct effects on cancer cells. Currently it remains unclear if turmeric
or curcumin has a role in preventing or treating human cancers. There are
several ongoing studies in this area. C
Cognitive function
Curcumin has been shown to
have antioxidant and anti-inflammatory properties and to reduce beta-amyloid
and plaque burden in lab studies. However, there is currently not enough
evidence to suggest the use of curcumin for cognitive performance.
C
Dyspepsia (heartburn)
Turmeric has been traditionally
used to treat stomach problems (such as indigestion from a fatty meal).
There is preliminary evidence that turmeric may offer some relief from
these stomach problems. However, at high doses or with prolonged use, turmeric
may actually irritate or upset the stomach. Reliable human research is
necessary before a recommendation can be made. C
Gallstone prevention/bile
flow stimulant
It has been said that there
are fewer people with gallstones in India, which is sometimes credited
to turmeric in the diet. Early studies report that curcumin, a chemical
in turmeric, may decrease the occurrence of gallstones. However, reliable
human studies are lacking in this area. The use of turmeric may be inadvisable
in patients with active gallstones. C
High cholesterol
Early studies suggest that
turmeric may lower levels of low-density lipoprotein ("bad cholesterol")
and total cholesterol in the blood. Better human studies are needed before
a recommendation can be made. C
HIV/AIDS
Several laboratory studies
suggest that curcumin, a component of turmeric, may have activity against
HIV. However, reliable human studies are lacking in this area. C
Inflammation
Laboratory and animal studies
show anti-inflammatory activity of turmeric and its constituent curcumin.
Reliable human research is lacking. C
Irritable bowel syndrome
(IBS)
Irritable bowel syndrome
(IBS) is a common functional disorder for which there are limited reliable
medical treatments. One study investigated the effects of Curcuma
xanthorriza on IBS and found that treatment did not show any therapeutic
benefit over placebo. More studies are needed to verify these findings.
C
Liver protection
In traditional Indian Ayurvedic
medicine, turmeric has been used to tone the liver. Early research suggests
that turmeric may have a protective effect on the liver, but more research
is needed before any recommendations can be made. C
Oral leukoplakia
Results from lab and animal
studies suggest turmeric may have anticancer effects. Large, well-designed
human studies are needed before a recommendation can be made. C
Osteoarthritis
Turmeric has been used historically
to treat rheumatic conditions. Laboratory and animal studies show anti-inflammatory
activity of turmeric and its constituent curcumin, which may be beneficial
in people with osteoarthritis. Reliable human research is lacking.
C
Peptic ulcer disease (stomach
ulcer)
Turmeric has been used historically
to treat stomach and duodenal ulcers. However, at high doses or with prolonged
use, turmeric may actually further irritate or upset the stomach. Currently,
there is not enough human evidence to make a firm recommendation.
C
Rheumatoid arthritis
Turmeric has been used historically
to treat rheumatic conditions and based on animal research may reduce inflammation.
Reliable human studies are necessary before a recommendation can be made
in this area. C
Scabies
Historically, turmeric has
been used on the skin to treat chronic skin ulcers and scabies. It has
also been used in combination with the leaves of the herb Azadirachta
indica ADR or "neem." More research is necessary before a firm recommendation
can be made. C
Uveitis (eye inflammation)
Laboratory and animal studies
show anti-inflammatory activity of turmeric and its constituent curcumin.
A poorly designed human study suggests a possible benefit of curcumin in
the treatment of uveitis. Reliable human research is necessary before a
firm conclusion can be drawn. C
Viral infection
Evidence suggests that turmeric
may help treat viral infections. However, there is not enough human evidence
in this area. Well-designed trials are needed to determine if these claims
are true. C
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